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Extracting Iboga Root Barks

by ASDFASC 2022. 8. 15.

 

There are several different ways to extract iboga root barks. These methods include using a coffee filter or funnel and repeating the procedure twice a day. After completing the procedure, bury the barks in the ground. Another method involves heating them in an oven at 200degF and scraping them off with a knife. Then, you can wrap them in foil and place them into empty capsules.

TA extract

The TA extract from iboga root carries an energetic charge that travels through the nervous system and heals a particular location. This energetic charge also helps close a door to old emotions. Our minds tend to think in twisted ways. Those distorted views are based on past experiences. Taking iboga in tincture form is a highly effective way to use it for therapeutic purposes.

 

In a recent study, Sadoon and colleagues at the Institute of Pharmacopoeia and Traditional Medicine in Libreville, Gabon, prepared a TA extract from iboga root-bark. They ground the bark chips into a powder using a coffee grinder, macerated them in water for 24 h, and then filtered the solution twice. After filtering, the root bark extract was adjusted to pH 9 with ammonium hydroxide and chloroform. The extract was then concentrated five times using chloroform in a fume hood.

ibogaine

Iboga root barks contain ibogaaine, a substance that is found in large quantities in the plant. However, the plant is hard to consume. One kilogram of the root bark is used in a traditional Bwiti initiation ceremony. While different providers have different philosophies regarding the dosage, a typical therapeutic dose ranges from five to 100 grams. Because the plant contains a lot of fiber, it may cause a person to feel queasy or vomit.

 

Iboga is illegal in the United States, but it has been used in some African cultures for millennia. The plant is widely used in ceremonies in Gabon and Cameroon. Researchers found that the root bark contains a substance called ibogaine, which has therapeutic properties for treating addiction. Ibogaine has anti-addiction properties and a unique ability to ameliorate withdrawal symptoms from opioids. In addition to being a powerful anti-addictive, ibogaine is a general wellness tonic.

voacangine

In a recent study, researchers isolated voacangine from iboga seeds. This compound is a precursor to iboga scaffold and was found to be present in about 0.8% of the root bark's dried weight. The other major alkaloids isolated from the root barks included voacamine, voacamidine, and iboga-vobasinyl dimers. These alkaloids were further purified through optimized cleavage procedures.

 

The isolated voacangine and voacristine constituted a minimum of 0.88% of the dry weight of the root barks. The remaining voacamine, voacamidine, and iboga root barks also contained minor, unidentified alkaloids. Three of these were fully characterized by NMR. The concentration of tabernaricatine G was 0.07 g/g.

3-O-caffeoylquinic acid

In the laboratory, Sadoon et al. used a high-resolution mass spectrometry (HR-MS) approach to identify 30 indole alkaloids in T. iboga root barks. In addition to ibogaine, the researchers identified seven other compounds as constituents of T. iboga. These compounds were then extracted five times in chloroform in a fume hood to isolate 3-O-caffeoylquinic acid.

 

To obtain the alkaloids in iboga, the roots and inner barks are harvested from mature plants. The harvesting process is time-consuming and involves uprooting the entire shrub. This process also allows the plant to regenerate, preserving its medicinal value. But there are many disadvantages. Among them are:

TA-extracted ibogaine

TA-extracted ibogaine is extracted from iboga root bark by a process that mimics the natural balance of the plant. The therapeutic effects of TA-extracted ibogaine are best achieved by using TA extracts that reflect the balance of the root bark. The bark itself is a bitter substance that can make people feel nauseous or even physically ill. Raw iboga root bark is typically used as an adjunct to other treatments or as a booster dose after an acute treatment episode. It is digested much more slowly and produces a longer-lasting effect.

 

TA extracts contain the full range of alkaloids and are easier to use and cheaper than other forms of iboga. They also do not produce the dizziness and gastrointestinal disturbances that the root bark does. TA also uses a less toxic form of the plant, and so is better for the environment. TA extracts are not as potent as iboga root bark, and the dose is much easier to take.